SSBH 2023

Day 2 May 19(Fri) 09:00-10:00	Oral Presentation 1 [Clinical] E Room 1

Chair(s): Kyuri Hwang (Seoul National University, Korea), Ji-Wan Kim (University of Ulsan, Korea)

09:00-09:10	Imminent Fracture Prediction Using Hip Computational Tomography-Based 2.5-Dimensional Deep-Learning Algorithm Sung Hye Kong (Seoul National University, Korea)
09:10-09:20	Fracture Risk Prediction and Assessment from 2D-DXA Scan by Augmented Gradient Boosting Algorithm Heesun Choi (Ewha Womans University, Korea)
09:20-09:30	Development of Mini K-FRAX Tool to Predict Imminent Risk of Fractures in Korean Elderly Women So Young Park (Kyung Hee University, Korea)
09:30-09:40	Association between Frailty and the Risk of Osteoporotic Fracture: The Chungju Metabolic Disease Cohort Study Jeongmin Lee (The Catholic University of Korea, Korea)
09:40-09:50	Genetically Determined Caffeine Intake and Bone Mineral Density: A Two-Sample Mendelian Randomization Study Gloria Hoi-Yee Li (The Hong Kong Polytechnic University, Hong Kong)
09:50-10:00	Associations between Use of Anti-Resorptive Agents for Patients with Osteoporosis and All-Cause Mortality Risk: A Nationwide Population-Based Study Kyoung Jin Kim (Korea University, Korea)

Day 2 May 19(Fri) 10:05-10:55	Plenary Lecture 1 E Room 1

We invited Dr. David Rowe (Director of the Center for Regenerative Medicine and Skeletal Development at the University of Connecticut) to be a basic science keynote speaker at SSBH 2023. Dr. Rowe is a distinguished researcher whose work has significantly influenced the development of bone, cartilage, and tendon through cellular differentiation. He has created and generously donated multiple bone cell-specific fluorescent protein-expressing mice, including osteocalcin- and Col1a1-GFP mice, which have become indispensable resources for researchers in skeletal biology. In addition, Dr. Rowe is leading the University of Connecticut's Bonebase program, which provides a platform for sharing his mouse phenotyping big data, mouse lines, and methodologies with other researchers.
Dr. Rowe’s research impacted the cellular differentiation of bone, cartilage, and tendon development. In particular, he has created and donated multiple bone cell-specific fluorescent protein-expressing mice such as osteocalcin- and Col1a1- GFP mice, which are crucial resources for skeletal biology researchers. Dr. Rowe spearheads the University of Connecticut’s Bonebase program to share his mouse phenotyping big data, mouse lines and methodologies.

Chair(s): Hyun-Mo Ryoo (Seoul National University, Korea)

10:05-10:55	Preparing Basic Skeletal Biology Research for the Big Data Arena David W. Rowe (University of Connecticut, USA)

Day 2 May 19(Fri) 11:10-12:25	Symposium 1. Bone Health at Different Stages of Life E Room 1

Jung Sub Lim from Korea Cancer Center Hospital will introduce the practice guidelines for optimizing bone health in Korean children and adolescents which published on 2022 by the Committee on Pediatric Bone Health of the Korean Society of Pediatric Endocrinology.
These guidelines include processes of bone acquisition, definition, and evaluation of low bone mineral density (BMD), causes of osteoporosis, methods for optimizing bone health, and pharmacological treatments for enhancing BMD in children and adolescent.
Adi Cohen from Columbia University will introduce dilemmas commonly encountered in diagnosis, investigation, and management of osteoporosis in younger adults. She will introduce a suggested framework, based on the limited available evidence and supported by clinical experience, for the diagnosis, assessment, and management of osteoporosis in young adults. Youn-Jee Chung will introduce the role of hormone therapy in postmenopausal women in clinical setting. We hope this session will provide an opportunity to share an overall approach and management know-how for lifelong bone health.

Chair(s): Deog Yoon Kim (Kyung Hee University, Korea), Jung-Ho Shin (Korea University, Korea)

11:10-11:35	Clinical Practice Guidelines for Optimizing Bone Health in Korean Children and Adolescents Jung Sub Lim (Korea Cancer Center Hospital, Korea)
11:35-12:00	Dilemmas in the Management of Osteoporosis in Younger Adults Adi Cohen (Columbia University, USA)
12:00-12:25	The Role of Hormone Therapy in Postmenopausal Women Youn-Jee Chung (The Catholic University of Korea, Korea)

Day 2 May 19(Fri) 12:25-12:40	Luncheon Symposium 1 E Room 1

Chair(s): Dong Won Byun (Soonchunhyang University, Korea)

12:25-12:40	The Fast Path in Osteoporosis Treatment, Correcting the Course A Ram Hong (Chonnam National University, Korea)

Day 2 May 19(Fri) 13:25-14:40	KSBMR-ASBMR-JSBMR Joint Symposium E Room 1

We are pleased to announce that the 2023 SSBH will once again host a live lecture format for the joint symposium of KSBMR-ASBMR-JSBMR. Invited are three researchers, each representing their respective society, to share the latest insights on bone metabolism research, particularly on the basic research of skeletal aging. Dr. Ok Hee Jeon, representing KSBMR, has been researching the musculoskeletal system and cartilage's aging process since completing her postdoctoral training at Buck Institute for Research on Aging and joining Korea University College of Medicine. She is an active junior member of the KSBMR Scientific Committee and will present new data on the aging/regeneration process of the musculoskeletal system based on blood sharing between two mice, following her recent publication in Nature Endocrinology. Dr. Noriaki Ono, representing ASBMR, is a musculoskeletal stem cell researcher who completed his postdoctoral fellowship under Dr. Henry Kronenberg at Harvard Medical School. He recently relocated his laboratory from the University of Michigan School of Dentistry to the University of Texas and has published many high-profile papers on musculoskeletal stem cells. He will present new data on the differences between periosteal stem cells of young mice and those of aging mice at this symposium. Dr. Sumito Ogawa, representing JSBMR, will discuss the clinical aspects of age-related muscle loss, frailty, and prevention methods. With the joint symposium held in person due to COVID, it is expected that higher-level lectures and discussions can take place.

Chair(s): Mary L. Bouxsein (Massachusetts General Hospital, USA), Seiji Fukumoto (The University of Tokushima, Japan)

13:25-13:50	Heterochronic Blood Exchange: Triggers Aging in Musculoskeletal System Ok Hee Jeon (Korea University, Korea)
13:50-14:15	Bone Marrow Endosteal Stem/Stromal Cells in Young Bones: An Essential Regulator of Bone Health and Disease Noriaki Ono (University of Texas at Houston School of Dentistry, USA)
14:15-14:40	Age-Related Sarcopenia and Frailty with Its Preventive Approaches Sumito Ogawa (Tokyo University, Japan)

Day 2 May 19(Fri) 14:40-15:30	Plenary Lecture 2 E Room 1

Professor Steven R. Cummings is currently Director of San Francisco Coordinating Center and Emeritus Professor of Medicine, Epidemiology and Biostatistics at University of California, San Francisco. He is an internationally recognized expert on the epidemiology of osteoporosis, women's health, and aging. Goal-directed treatment, also called treat to target, is a strategy that has a clear goal and changes treatment if the goal is not achieved. Recently, it has been proposed as a strategy to assist clinicians in selecting the most appropriate initial treatment for osteoporosis and guiding subsequent decisions to continue, change, or stop treatment. In this plenary session, he will give us an informative lecture about goal-directed treatment for osteoporosis.

Chair(s): Ho-Yeon Chung (Kyung Hee University, Korea)

14:40-15:30	Goal-Directed Treatment for Osteoporosis Steven R. Cummings (San Francisco Coordinating Center, California Pacific Medical Center Research Institute, USA)

Day 2 May 19(Fri) 15:45-17:00	Symposium 3. KSBMR-NHIS Joint Symposium K Room 1

Chair(s): Soon-Ae Shin (NHIS, Korea), Yong-Chan Ha (Bumin Hospital, Korea)

15:45-16:00	Method and Result of Osteoporosis Fracture Treatment Episode Construction Jaiyong Kim (National Health Insurance Service, Korea)
16:00-16:15	Trends of Osteoporotic Fracture in South Korea Young-Kyun Lee (Seoul National University, Korea)
16:15-16:30	COVID-19 and Osteoporotic Fracture HoeJeong Chung (Yonsei University Wonju College of Medicine, Korea)
16:30-16:45	Status in the Treatment of Osteoporosis and Osteoporotic Fracture Kyoung Min Kim (Yonsei University, Korea)
16:45-17:00	Q&A

Scientific Program